Across TCGA patient cohorts, ATP6AP1L mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP6AP1L-associated genes across cancer lineages are Rab25, ATM, and eIF4G. Each is linked with ATP6AP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6AP1L-to-partner and partner-to-ATP6AP1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6AP1L→partner) and Y-score (partner→ATP6AP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rab25 →	-0.467	-2.807	<.001	.003	3	2
UCEC	ATM →	-0.850	-2.415	<.001	.003	3	2
UCEC	eIF4G →	+0.313	+3.169	.012	.018	3	1
UCEC	A-Raf_pS299 →	-0.113	-2.321	.018	.034	3	1
UCEC	FoxM1 →	+0.263	+3.169	.011	.018	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.496	+1.906	.015	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

ATP6AP1L survival (RNA) · tumor vs normal (RNA) · all ATP6AP1L data types