Across TCGA cell cohorts, ATP6AP1L mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP6AP1L-associated genes across cancer lineages are LGI1, CSHL1, and CBLN4. Each is linked with ATP6AP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP6AP1L-to-partner and partner-to-ATP6AP1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP6AP1L→partner) and Y-score (partner→ATP6AP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LGI1 →	+0.096	+4.539	<.001	.007	3	1
BLOOD_Leukemia	CSHL1 →	+0.013	+4.539	.006	.007	3	1
BLOOD_Leukemia	CBLN4 →	+0.004	+4.539	<.001	.007	3	1
SKIN	OXT →	+0.063	+4.977	<.001	.007	3	1
SKIN	RETNLB →	+0.037	+4.977	<.001	.007	3	1
SKIN	GALP →	+0.022	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ATP6AP1L survival (RNA) · tumor vs normal (RNA) · all ATP6AP1L data types