ATP5PO

Across TCGA patient cohorts, ATP5PO mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5PO-associated genes across cancer lineages are RNU6-1233P, RBMY1J, and MIR7849. Each is linked with ATP5PO in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5PO-to-partner and partner-to-ATP5PO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1233P grouped by ATP5PO-low versus ATP5PO-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5PO→partner) and Y-score (partner→ATP5PO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1233P →	+0.653	+7.816	<.001	.008	3	1
SKCM	RBMY1J →	+0.014	+7.816	<.001	.008	3	1
UCEC	MIR7849 →	+1.064	+5.133	<.001	.008	3	1
UCEC	RNU105C →	+0.281	+5.484	<.001	.005	3	1
UCEC	RNU4-58P →	+0.574	+5.133	<.001	.008	3	1
UCEC	RNU6-271P →	+0.740	+5.852	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

RNU6-1233P by ATP5PO expression — SKCM

Explore this box plot interactively →