ATP5F1E

Across TCGA patient cohorts, ATP5F1E protein abundance is significantly associated with the RNA expression of many other genes, with 7,576 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATP5F1E-associated genes across cancer lineages are CXCR2, FCGR3B, and CXCR1. Each is linked with ATP5F1E in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP5F1E-to-partner and partner-to-ATP5F1E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP5F1E versus CXCR2 in PDAC, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1E→partner) and Y-score (partner→ATP5F1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CXCR2 →	-1.252	-0.828	<.001	<.001	3	7
PDAC	FCGR3B →	-1.246	-0.498	<.001	<.001	3	5
HNSC	CXCR1 →	-1.252	-0.754	<.001	<.001	3	5
PDAC	CMTM2 →	-0.741	-0.633	<.001	.002	3	4
BRCA	DCBLD1 →	-0.548	-0.453	<.001	<.001	3	4
COAD	RGS19 →	-0.494	-0.299	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,576 associations by consensus.

ATP5F1E vs CXCR2 — PDAC

Explore this scatter interactively →