ATP5F1E

Across TCGA patient cohorts, ATP5F1E mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5F1E-associated genes across cancer lineages are RN7SL134P, SNORA74C-1, and OR4C46. Each is linked with ATP5F1E in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5F1E-to-partner and partner-to-ATP5F1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by ATP5F1E-low versus ATP5F1E-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1E→partner) and Y-score (partner→ATP5F1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.354	+4.184	<.001	.003	3	1
UCEC	SNORA74C-1 →	+0.463	+4.671	.005	.001	3	1
COAD	OR4C46 →	+0.179	+7.741	<.001	.009	3	1
UCEC	RNU4-4P →	+0.555	+3.778	.007	.007	3	1
UCEC	RNU6-73P →	+0.370	+4.641	<.001	.006	3	1
UCEC	TRAJ57 →	+0.810	+3.903	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

RN7SL134P by ATP5F1E expression — UCEC

Explore this box plot interactively →