ATP5F1E

Across TCGA cell cohorts, ATP5F1E RNA expression is significantly associated with the go_rna of many other GO terms, with 3,668 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP5F1E-associated GO terms across cancer lineages are Negative regulation of t-circle formation, Regulation of telomeric loop disassembly, and Nucleoside triphosphate biosynthetic process. Each is linked with ATP5F1E in more than 8 cancer types. Because this analysis shows association rather than direction, both ATP5F1E-to-partner and partner-to-ATP5F1E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of t-circle formation grouped by ATP5F1E-low versus ATP5F1E-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1E→partner) and Y-score (partner→ATP5F1E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of t-circle formation →	+0.123	+1.201	.002	.002	3	9
SOFT_TISSUE	Regulation of telomeric loop disassembly →	+0.109	+0.744	<.001	.006	3	9
SKIN	Nucleoside triphosphate biosynthetic process →	+0.087	+0.780	<.001	<.001	3	9
SKIN	Response to dehydroepiandrosterone →	+0.203	+0.736	.009	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.143	+0.924	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Spliceosomal tri-snRNP complex assembly →	+0.079	+0.695	.004	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,668 associations by consensus.

Negative regulation of t-circle formation by ATP5F1E expression — BREAST

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