ATP5F1D

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP5F1D mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5F1D-associated genes across cancer lineages are RNU6-591P and RN7SKP135. Each is linked with ATP5F1D in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5F1D-to-partner and partner-to-ATP5F1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by ATP5F1D-low versus ATP5F1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1D→partner) and Y-score (partner→ATP5F1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNU6-591P →+0.652+8.066<.001.00731
UCECRN7SKP135 →+0.173+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RNU6-591P by ATP5F1D expression — UCEC

Box plot of RNU6-591P in ATP5F1D-low vs ATP5F1D-high samples in UCEC.

Explore this box plot interactively →

Exploration