ATP5F1D

Across TCGA cell cohorts, ATP5F1D RNA expression is significantly associated with the go_rna of many other GO terms, with 3,397 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP5F1D-associated GO terms across cancer lineages are Cytoplasm protein quality control by the ubiquitin-proteasome system, Energy coupled proton transmembrane transport, against electrochemical gradient, and Electron transport coupled proton transport. Each is linked with ATP5F1D in more than 17 cancer types. Because this analysis shows association rather than direction, both ATP5F1D-to-partner and partner-to-ATP5F1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasm protein quality control by the ubiquitin-proteasome system grouped by ATP5F1D-low versus ATP5F1D-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1D→partner) and Y-score (partner→ATP5F1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.206	+0.731	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.102	+0.702	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Electron transport coupled proton transport →	+0.102	+0.702	<.001	.001	3	17
BONE	Cytoplasm protein quality control →	+0.169	+0.724	<.001	<.001	3	14
PANCREAS	Enzyme-directed rRNA pseudouridine synthesis →	+0.089	+0.582	.001	.001	3	11
URINARY_TRACT	Positive regulation of protein localization to chromatin →	+0.091	+0.631	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,397 associations by consensus.

Cytoplasm protein quality control by the ubiquitin-proteasome system by ATP5F1D expression — BONE

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