ATP5F1B

Across TCGA patient cohorts, ATP5F1B mutation is significantly associated with the RNA expression of many other genes, with 447 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP5F1B-associated genes across cancer lineages are MIR8082, NEGR1-IT1, and EPPIN-WFDC6. Each is linked with ATP5F1B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP5F1B-to-partner and partner-to-ATP5F1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8082 grouped by ATP5F1B-low versus ATP5F1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP5F1B→partner) and Y-score (partner→ATP5F1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8082 →	+0.329	+2.424	.001	.005	3	2
BLCA	NEGR1-IT1 →	+0.085	+6.307	<.001	<.001	3	2
BLCA	EPPIN-WFDC6 →	+0.482	+4.463	<.001	.005	3	2
LGG	MIR3973 →	+0.431	+5.148	<.001	.007	3	2
LIHC	CSH1 →	+0.016	+4.564	.001	.006	3	2
LIHC	SNORA24B →	+0.298	+4.689	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 447 associations by consensus.

MIR8082 by ATP5F1B expression — UCEC

Explore this box plot interactively →