ATP2B2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP2B2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,617 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATP2B2-associated genes across cancer lineages are SCN1B, DLGAP3, and MXI1. Each is linked with ATP2B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2B2-to-partner and partner-to-ATP2B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP2B2 versus SCN1B in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B2→partner) and Y-score (partner→ATP2B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSCN1B →+0.513+0.563<.001<.00132
GBMDLGAP3 →+1.365+0.887<.001<.00132
CCRCCMXI1 →+0.811+0.494.001.00132
GBMLSM11 →+0.435+0.737<.001<.00132
CCRCCIL24 →-0.391-0.436<.001.00832
CCRCCZNF572 →+0.409+0.315.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,617 associations by consensus.

ATP2B2 vs SCN1B — GBM

Per-sample scatter of ATP2B2 vs SCN1B in GBM (Pearson r = 0.43).

Explore this scatter interactively →

Exploration