ATP2B2

Across TCGA cell cohorts, ATP2B2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,034 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ATP2B2-associated GO terms across cancer lineages are Regulation of myoblast fusion, Protein folding, and Positive regulation of cytoplasmic translation. Each is linked with ATP2B2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP2B2-to-partner and partner-to-ATP2B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by ATP2B2-low versus ATP2B2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B2→partner) and Y-score (partner→ATP2B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of myoblast fusion →	+0.049	+0.302	.001	.005	2	7
LUNG_NSCLC_LUSC	Protein folding →	+0.065	+0.102	.004	.004	3	5
LUNG_SCLC	Positive regulation of cytoplasmic translation →	+0.085	+1.192	.005	.006	2	6
UPPER_AERODIGESTIVE_TRACT	Cellular response to nutrient levels →	+0.056	+0.030	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to organelle →	+0.058	+0.038	<.001	<.001	3	4
LUNG_SCLC	Nucleoside triphosphate metabolic process →	+0.094	+1.471	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,034 associations by consensus.

Regulation of myoblast fusion by ATP2B2 expression — CNS

Explore this box plot interactively →