ATP2B2

Across TCGA cell cohorts, ATP2B2 mutation is significantly associated with the RNA expression of many other genes, with 276 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP2B2-associated genes across cancer lineages are SCGB1C1, PPP2R5E, and PPY. Each is linked with ATP2B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2B2-to-partner and partner-to-ATP2B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1C1 grouped by ATP2B2-low versus ATP2B2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B2→partner) and Y-score (partner→ATP2B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SCGB1C1 →	+0.242	+4.981	<.001	.008	3	2
LUNG_NSCLC_LUAD	PPP2R5E →	+0.477	+3.115	.008	.009	3	2
OVARY	PPY →	+0.187	+4.444	<.001	.001	3	2
OVARY	TSPY2 →	+0.010	+4.222	<.001	.006	3	2
LARGE_INTESTINE	FAM86B1 →	+0.811	+2.459	.007	.006	3	2
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 276 associations by consensus.

SCGB1C1 by ATP2B2 expression — CNS

Explore this box plot interactively →