ATP2B1

Across TCGA cell cohorts, ATP2B1 mutation is significantly associated with the RNA expression of many other genes, with 502 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP2B1-associated genes across cancer lineages are OR2AJ1, ZMYM6, and HAO1. Each is linked with ATP2B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP2B1-to-partner and partner-to-ATP2B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2AJ1 grouped by ATP2B1-low versus ATP2B1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP2B1→partner) and Y-score (partner→ATP2B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2AJ1 →	+0.042	+4.867	<.001	.009	3	2
LARGE_INTESTINE	ZMYM6 →	+0.472	+3.321	.003	.003	3	2
OESOPHAGUS	HAO1 →	+0.023	+4.906	<.001	.006	3	1
OESOPHAGUS	MINDY4B →	+0.070	+4.906	<.001	.006	3	1
LUNG_SCLC	OR52E8 →	+0.040	+4.643	<.001	.004	3	1
LUNG_SCLC	KRTAP9-1 →	+0.171	+4.044	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 502 associations by consensus.

OR2AJ1 by ATP2B1 expression — BLOOD_Lymphoma

Explore this box plot interactively →