ATP12A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP12A protein abundance is significantly associated with the RNA expression of many other genes, with 1,559 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATP12A-associated genes across cancer lineages are ANKDD1B, GCAT, and LMF2. Each is linked with ATP12A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP12A-to-partner and partner-to-ATP12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP12A versus ANKDD1B in PDAC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP12A→partner) and Y-score (partner→ATP12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACANKDD1B →+0.763+0.653<.001<.00132
PDACGCAT →+0.528+0.655.001.00131
PDACLMF2 →+0.273+0.473.005.00531
PDACNFATC4 →-0.421-0.598.008.00431
PDACRNF125 →-0.588-0.711.008.00231
PDACPARD6A →+0.522+0.513<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,559 associations by consensus.

ATP12A vs ANKDD1B — PDAC

Per-sample scatter of ATP12A vs ANKDD1B in PDAC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration