ATP11A

Across TCGA cell cohorts, ATP11A mutation is significantly associated with the RNA expression of many other genes, with 153 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP11A-associated genes across cancer lineages are CD300LD, SERPINA11, and C8orf74. Each is linked with ATP11A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP11A-to-partner and partner-to-ATP11A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300LD grouped by ATP11A-low versus ATP11A-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP11A→partner) and Y-score (partner→ATP11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CD300LD →	+0.041	+3.285	.003	.009	3	2
LUNG_SCLC	SERPINA11 →	+1.544	+4.044	<.001	.009	3	2
BREAST	C8orf74 →	+0.180	+4.421	<.001	.004	3	2
CNS	TBATA →	+0.023	+6.357	<.001	<.001	3	2
STOMACH	SPINK14 →	+0.433	+5.285	<.001	.003	3	2
LARGE_INTESTINE	BTNL2 →	+0.030	+2.830	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 153 associations by consensus.

CD300LD by ATP11A expression — BLOOD_Myeloma

Explore this box plot interactively →