ATP10D

Across TCGA cell cohorts, ATP10D mutation is significantly associated with the RNA expression of many other genes, with 1,096 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP10D-associated genes across cancer lineages are AKAP3, ZNF24, and ADO. Each is linked with ATP10D in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP10D-to-partner and partner-to-ATP10D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AKAP3 grouped by ATP10D-low versus ATP10D-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP10D→partner) and Y-score (partner→ATP10D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AKAP3 →	+0.436	+3.364	<.001	.002	3	3
LARGE_INTESTINE	ZNF24 →	+0.619	+3.459	.001	.001	3	3
LARGE_INTESTINE	ADO →	+0.458	+3.043	<.001	<.001	3	3
LARGE_INTESTINE	ACADSB →	+0.917	+2.364	<.001	<.001	3	3
SKIN	DOCK3 →	+0.661	+3.451	<.001	.002	3	2
BLOOD_Leukemia	KCNA6 →	+0.998	+3.426	.006	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,096 associations by consensus.

AKAP3 by ATP10D expression — SKIN

Explore this box plot interactively →