ATP10D

Across TCGA pan-cancer cohorts, ATP10D RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ATP10D’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ATP10D RNA is repressed in tumor relative to normal tissue. In most cancer types ATP10D is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA, HNSC, and UCEC are the cancer types where ATP10D tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATP10D RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.524	<.001	9	view →
HNSC	All	All	+0.719	<.001	9	view →
UCEC	All	All	−1.375	<.001	6	view →
LUAD	All	All	−0.261	.014	6	view →
LIHC	Female	III,IV	+0.635	.002	5	view →
KIRP	Male	All	−0.508	.024	5	view →
KIRC	All	II,III,IV	−0.385	.004	5	view →
BRCA	Female	All	−0.371	<.001	4	view →
CHOL	All	All	+1.132	.001	3	view →
PRAD	All	All	−0.348	.012	2	view →
READ	Female	All	−0.713	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ATP10D–THCA

Open the THCA breakdown →