ATP10D

Across TCGA pan-cancer cohorts, ATP10D RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ATP10D data layer compared with 10 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ATP10D RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ATP10D expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

KIRC, ACC, and HNSC are the cancer types where ATP10D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.732	0.534	<.001	107	view →
ACC	OS	Quartile	II,III,IV	0.686	0.961	.002	63	view →
HNSC	OS	Quartile	III,IV	0.144	0.532	.003	51	view →
LGG	OS	Median	All	0.374	0.526	<.001	47	view →
BRCA	OS	Tertile	All	0.982	0.948	.003	31	view →
UVM	DFS	Quartile	III,IV	0.232	0.900	.002	22	view →
LIHC	OS	Median	All	0.730	0.818	.017	18	view →
PCPG	OS	Tertile	All	0.779	1.000	.023	16	view →
ESCA	OS	Tertile	All	1.000	0.563	.017	15	view →
THCA	OS	Quartile	All	0.940	1.000	.013	14	view →
UCS	DFS	Tertile	IV	0.938	0.361	.024	12	view →
UCEC	OS	Quartile	All	0.897	0.954	.016	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ATP10D–KIRC (DFS)

Open the KIRC breakdown →