Across TCGA cell cohorts, ATP10A mutation is significantly associated with the RNA expression of many other genes, with 1,556 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP10A-associated genes across cancer lineages are ZNF286A, GRK7, and KCNRG. Each is linked with ATP10A in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP10A-to-partner and partner-to-ATP10A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP10A→partner) and Y-score (partner→ATP10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF286A →	+1.104	+3.411	.007	.003	3	3
LARGE_INTESTINE	GRK7 →	+0.054	+1.666	.006	.001	3	3
LUNG_NSCLC_LUAD	KCNRG →	+0.219	+3.280	.001	.004	3	3
LARGE_INTESTINE	GIT1 →	+0.526	+3.321	.002	.002	3	3
LARGE_INTESTINE	PRPSAP2 →	+0.574	+2.764	<.001	<.001	3	3
LARGE_INTESTINE	CTC1 →	+0.653	+2.000	.002	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,556 associations by consensus.

Exploration

ATP10A survival (RNA) · tumor vs normal (RNA) · all ATP10A data types