ATG9B

Across TCGA cell cohorts, ATG9B mutation is significantly associated with the RNA expression of many other genes, with 374 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG9B-associated genes across cancer lineages are CBY1, JOSD1, and EIF3D. Each is linked with ATG9B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG9B-to-partner and partner-to-ATG9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by ATG9B-low versus ATG9B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG9B→partner) and Y-score (partner→ATG9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.608	+3.299	.002	.004	3	1
LARGE_INTESTINE	JOSD1 →	+0.652	+3.212	.001	.006	3	1
LARGE_INTESTINE	EIF3D →	+0.437	+3.137	.006	.007	3	1
LARGE_INTESTINE	RNF125 →	+1.283	+3.212	<.001	.006	3	1
LARGE_INTESTINE	NISCH →	+0.772	+3.212	.002	.006	3	1
LARGE_INTESTINE	ERI1 →	+0.779	+3.212	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 374 associations by consensus.

CBY1 by ATG9B expression — LARGE_INTESTINE

Explore this box plot interactively →