ATG9B

Across TCGA pan-cancer cohorts, ATG9B RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ATG9B’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ATG9B RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATG9B is over-expressed in tumor.

COAD, KIRC, and LUAD are the cancer types where ATG9B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATG9B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+2.391	<.001	12	view →
KIRC	Female	All	+0.980	<.001	11	view →
LUAD	Female	II,III,IV	+1.239	<.001	9	view →
BLCA	Male	III,IV	+1.738	<.001	6	view →
BRCA	All	III,IV	+0.576	<.001	6	view →
READ	All	All	+1.688	<.001	5	view →
CHOL	All	All	+0.954	<.001	4	view →
LUSC	Male	All	+0.883	<.001	4	view →
THCA	Male	II,III,IV	+0.308	.003	4	view →
LIHC	All	All	+0.220	.005	3	view →
PRAD	All	All	+0.396	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ATG9B–COAD

Open the COAD breakdown →