ATG4D

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATG4D protein abundance is significantly associated with the RNA expression of many other genes, with 5,193 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATG4D-associated genes across cancer lineages are ACP7, RNU6-1138P, and DLG5-AS1. Each is linked with ATG4D in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG4D-to-partner and partner-to-ATG4D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG4D versus ACP7 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG4D→partner) and Y-score (partner→ATG4D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCACP7 →+1.155+0.448<.001<.00132
GBMRNU6-1138P →+1.221+0.577.001<.00132
GBMDLG5-AS1 →+0.904+0.791.007<.00132
LSCCTXNP4 →+0.442+0.568.001<.00132
GBMGTSE1-DT →+0.490+0.388.006.00432
GBMRCN1 →-0.552-0.577.004<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,193 associations by consensus.

ATG4D vs ACP7 — LSCC

Per-sample scatter of ATG4D vs ACP7 in LSCC (Pearson r = 0.46).

Explore this scatter interactively →

Exploration