ATG2A

Across TCGA cell cohorts, ATG2A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,004 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATG2A-associated GO terms across cancer lineages are Positive regulation of autophagy, Transcription pausing by RNA polymerase II, and Vacuole organization. Each is linked with ATG2A in more than 17 cancer types. Because this analysis shows association rather than direction, both ATG2A-to-partner and partner-to-ATG2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy grouped by ATG2A-low versus ATG2A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG2A→partner) and Y-score (partner→ATG2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of autophagy →	+0.076	+1.423	<.001	<.001	3	18
BONE	Transcription pausing by RNA polymerase II →	+0.167	+0.877	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.063	+1.152	<.001	<.001	3	15
STOMACH	Vacuolar transport →	+0.090	+0.852	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.079	+1.149	<.001	.002	3	15
SOFT_TISSUE	Retrograde transport, endosome to Golgi →	+0.054	+0.640	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,004 associations by consensus.

Positive regulation of autophagy by ATG2A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →