ATG2A

Across TCGA pan-cancer cohorts, ATG2A RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ATG2A’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ATG2A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ATG2A is over-expressed in tumor.

HNSC, STAD, and LUSC are the cancer types where ATG2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATG2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.648	<.001	11	view →
STAD	Male	II,III,IV	+1.200	<.001	8	view →
LUSC	Male	III,IV	+0.839	.030	1	view →
ESCA	All	All	+0.751	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ATG2A–HNSC

Open the HNSC breakdown →