Across TCGA patient cohorts, ATF7-NPFF RNA expression is significantly associated with the go_rna of many other GO terms, with 7,165 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ATF7-NPFF-associated GO terms across cancer lineages are Obsolete regulation of histone modification, Positive regulation of DNA repair, and Protein deacetylation. Each is linked with ATF7-NPFF in more than 27 cancer types. Because this analysis shows association rather than direction, both ATF7-NPFF-to-partner and partner-to-ATF7-NPFF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF7-NPFF→partner) and Y-score (partner→ATF7-NPFF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	Obsolete regulation of histone modification →	+0.056	+1.103	<.001	<.001	3	28
KIRC	Positive regulation of DNA repair →	+0.051	+1.150	<.001	<.001	3	28
KIRC	Protein deacetylation →	+0.060	+1.174	<.001	<.001	3	28
KIRC	Positive regulation of double-strand break repair →	+0.053	+1.142	<.001	<.001	3	27
KIRC	Regulation of DNA repair →	+0.042	+1.082	<.001	<.001	3	27
KIRC	Obsolete histone modification →	+0.056	+1.162	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

Exploration

ATF7-NPFF survival (RNA) · tumor vs normal (RNA) · all ATF7-NPFF data types