ATAT1

Across TCGA patient cohorts, ATAT1 mutation is significantly associated with the RNA expression of many other genes, with 2,819 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATAT1-associated genes across cancer lineages are RPS27P12, MIR3135A, and PNPLA10P. Each is linked with ATAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAT1-to-partner and partner-to-ATAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS27P12 grouped by ATAT1-low versus ATAT1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAT1→partner) and Y-score (partner→ATAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RPS27P12 →	+0.194	+4.969	<.001	.004	3	2
CESC	MIR3135A →	+0.648	+4.503	<.001	.005	3	2
BLCA	PNPLA10P →	+0.024	+5.177	<.001	.007	3	2
BLCA	RNA5SP137 →	+0.353	+5.685	<.001	.003	3	2
UCEC	RNU4-58P →	+0.164	+2.417	<.001	<.001	3	2
COAD	RAB9AP4 →	+0.105	+5.409	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,819 associations by consensus.

RPS27P12 by ATAT1 expression — CESC

Explore this box plot interactively →