ATAD2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATAD2B mutation is significantly associated with the RNA expression of many other genes, with 4,093 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATAD2B-associated genes across cancer lineages are RNU6ATAC10P, RNA5SP49, and H2AC12. Each is linked with ATAD2B in more than 2 cancer types. Because this analysis shows association rather than direction, both ATAD2B-to-partner and partner-to-ATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6ATAC10P grouped by ATAD2B-low versus ATAD2B-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD2B→partner) and Y-score (partner→ATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRNU6ATAC10P →+0.445+5.257<.001.00233
BRCARNA5SP49 →+0.078+4.064<.001.00833
COADH2AC12 →+1.065+3.223<.001.00833
LIHCSYF2P1 →+0.070+4.293<.001.00933
SKCMMIR4797 →+0.268+2.715.002.00433
UCECLIN54 →+0.368+1.373<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,093 associations by consensus.

RNU6ATAC10P by ATAD2B expression — READ

Box plot of RNU6ATAC10P in ATAD2B-low vs ATAD2B-high samples in READ.

Explore this box plot interactively →

Exploration