ATAD2B

Across TCGA patient cohorts, ATAD2B mutation is significantly associated with the total protein of many other genes, with 57 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATAD2B-associated genes across cancer lineages are INPP4B, ATM, and Caspase-7-cleavedD198. Each is linked with ATAD2B in more than 2 cancer types. Because this analysis shows association rather than direction, both ATAD2B-to-partner and partner-to-ATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by ATAD2B-low versus ATAD2B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD2B→partner) and Y-score (partner→ATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.511	-2.991	.008	.036	3	2
COAD	ATM →	-0.698	-2.991	<.001	.036	2	3
COAD	Caspase-7-cleavedD198 →	+1.686	+3.008	<.001	.019	3	2
UCEC	eIF4E →	+0.131	+2.070	.024	.001	3	2
UCEC	GAPDH →	+0.308	+1.152	.037	.048	3	2
UCEC	JNK_pT183_Y185 →	-0.167	-2.058	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

INPP4B by ATAD2B expression — COAD

Explore this box plot interactively →