ATAD2B

Across TCGA cell cohorts, ATAD2B mutation is significantly associated with the RNA expression of many other genes, with 898 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATAD2B-associated genes across cancer lineages are OR4D6, OR6K3, and KRTAP22-2. Each is linked with ATAD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD2B-to-partner and partner-to-ATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4D6 grouped by ATAD2B-low versus ATAD2B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD2B→partner) and Y-score (partner→ATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	OR4D6 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	OR6K3 →	+0.006	+4.906	<.001	.006	3	1
SKIN	KRTAP22-2 →	+0.100	+4.437	<.001	.004	3	1
BLOOD_Leukemia	TAS2R7 →	+0.013	+3.185	<.001	.006	3	1
BLOOD_Leukemia	CABS1 →	+0.011	+3.984	<.001	.006	3	1
BLOOD_Leukemia	ALPI →	+0.003	+3.464	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 898 associations by consensus.

OR4D6 by ATAD2B expression — OESOPHAGUS

Explore this box plot interactively →