ATAD2B

Across TCGA cell cohorts, ATAD2B mutation is significantly associated with the mutation status of many other genes, with 7,131 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATAD2B-associated genes across cancer lineages are BCOR, PHF20L1, and SPG11. Each is linked with ATAD2B in more than 5 cancer types. Because this analysis shows association rather than direction, both ATAD2B-to-partner and partner-to-ATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BCOR grouped by ATAD2B-low versus ATAD2B-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD2B→partner) and Y-score (partner→ATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	BCOR →	+4.392	+4.954	.008	.008	1	6
BLOOD_Lymphoma	PHF20L1 →	+4.203	+2.710	.008	.008	1	6
UPPER_AERODIGESTIVE_TRACT	SPG11 →	+4.392	+4.954	.008	.008	1	6
BREAST	VPS13D →	+5.095	+4.442	.001	.001	1	5
CNS	TCF20 →	+5.277	+4.459	.005	.005	1	5
UPPER_AERODIGESTIVE_TRACT	SETD5 →	+5.392	+5.392	.004	.004	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,131 associations by consensus.

BCOR by ATAD2B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →