ASZ1

Across TCGA cell cohorts, ASZ1 RNA expression is significantly associated with the mutation status of many other genes, with 289 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASZ1-associated genes across cancer lineages are GHR, CACNA1G, and ZNF608. Each is linked with ASZ1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ASZ1-to-partner and partner-to-ASZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHR grouped by ASZ1-low versus ASZ1-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASZ1→partner) and Y-score (partner→ASZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GHR →	+2.479	+0.355	.008	<.001	3	3
LUNG_NSCLC_LUSC	CACNA1G →	+4.108	+0.089	.005	.008	3	2
BLOOD_Myeloma	ZNF608 →	+3.700	+0.136	<.001	.001	3	2
LUNG_NSCLC_LUSC	NOBOX →	+4.108	+0.089	.005	.008	3	2
BREAST	BCOR →	+3.898	+0.256	.005	<.001	3	2
OVARY	CUX2 →	+2.906	+0.058	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 289 associations by consensus.

GHR by ASZ1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →