ASXL2

Across TCGA patient cohorts, ASXL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,043 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ASXL2-associated proteins across cancer lineages are TSN, C1orf35, and NUP155. Each is linked with ASXL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ASXL2-to-partner and partner-to-ASXL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASXL2 versus TSN in UCEC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASXL2→partner) and Y-score (partner→ASXL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TSN →	+0.287	+0.352	.002	.005	2	5
LSCC	C1orf35 →	+0.529	+0.507	<.001	<.001	3	4
LSCC	NUP155 →	+0.149	+0.271	<.001	.005	3	4
LSCC	NUP93 →	+0.163	+0.265	.001	.006	3	4
LSCC	SLC4A1AP →	+0.365	+0.571	<.001	<.001	3	4
PDAC	SNRPD3 →	+0.372	+0.271	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,043 associations by consensus.

ASXL2 vs TSN — UCEC

Explore this scatter interactively →