Q-omics provides the consensus-scored ASS1P10 profile across patient tissues and cancer cell-line models. ASS1P10 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, ASS1P10 is differentially expressed in 10, with the highest sampling consensus in KIRP. Additionally, ASS1P10 RNA expression shows 13,470 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight UCEC, KIRP, and ESCA as cancer lineages where ASS1P10 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ASS1P10 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ASS1P10 survival associations across molecular data types. ASS1P10 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ASS1P10 RNA expression–survival associations across cancer types. High ASS1P10 expression shows unfavorable associations in UCEC, OV, MESO and THCA, but favorable associations in BLCA and KIRC. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify UCEC as the clearest survival context for ASS1P10 RNA expression.
This table summarizes ASS1P10 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for ASS1P10. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ASS1P10 shows lower tumor expression in KIRP, KICH and UCEC and higher tumor expression in KIRC, LUSC and STAD. The KIRP box plot shows higher ASS1P10 RNA expression in normal versus tumor tissue (log2 FC = −0.367, t-test p < 0.001).
This table shows molecular features associated with ASS1P10 in patient tissues and cancer cell lines. In patient samples, ASS1P10 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
