ASPN

Across TCGA patient cohorts, ASPN RNA expression is significantly associated with the protein abundance of many other proteins, with 19,429 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ASPN-associated proteins across cancer lineages are SERPINF1, SVIL, and CALD1. Each is linked with ASPN in more than 9 cancer types. Because this analysis shows association rather than direction, both ASPN-to-partner and partner-to-ASPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASPN versus SERPINF1 in BRCA, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPN→partner) and Y-score (partner→ASPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SERPINF1 →	+0.921	+1.866	<.001	<.001	3	10
UCEC	SVIL →	+0.502	+1.060	<.001	<.001	3	10
UCEC	CALD1 →	+1.015	+1.255	<.001	<.001	3	10
BRCA	FKBP7 →	+0.563	+2.083	<.001	<.001	3	10
BRCA	ISLR →	+0.759	+2.126	<.001	<.001	3	10
UCEC	KANK2 →	+0.759	+1.216	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,429 associations by consensus.

ASPN vs SERPINF1 — BRCA

Explore this scatter interactively →