ASPN

Across TCGA cell cohorts, ASPN RNA expression is significantly associated with the go_rna of many other GO terms, with 869 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible ASPN-associated GO terms across cancer lineages are mRNA export from nucleus, DNA biosynthetic process, and Mismatch repair. Each is linked with ASPN in more than 5 cancer types. Because this analysis shows association rather than direction, both ASPN-to-partner and partner-to-ASPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by ASPN-low versus ASPN-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASPN→partner) and Y-score (partner→ASPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	mRNA export from nucleus →	+0.084	+0.024	.001	.003	3	6
BLOOD_Myeloma	DNA biosynthetic process →	+0.052	+0.036	<.001	<.001	3	6
BLOOD_Myeloma	Mismatch repair →	+0.067	+0.047	.007	.004	2	6
LUNG_NSCLC_LUSC	RNA export from nucleus →	+0.080	+0.019	.002	.001	3	5
LARGE_INTESTINE	Centriole replication →	+0.052	+0.021	.005	.007	3	5
LUNG_NSCLC_LUSC	mRNA transport →	+0.085	+0.025	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 869 associations by consensus.

mRNA export from nucleus by ASPN expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →