ASIC1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ASIC1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,758 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ASIC1-associated genes across cancer lineages are FRMPD3, PDE6D, and GPR101. Each is linked with ASIC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASIC1-to-partner and partner-to-ASIC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ASIC1 versus FRMPD3 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASIC1→partner) and Y-score (partner→ASIC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMFRMPD3 →+0.768+0.575.004.00532
GBMPDE6D →+0.296+0.453<.001<.00132
GBMGPR101 →+0.231+0.560<.001.00132
GBMLINC02549 →+0.433+0.472<.001<.00132
GBMRPL36AP26 →+0.819+0.689.001.00132
GBMB3GAT1-DT →+0.726+0.738<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,758 associations by consensus.

ASIC1 vs FRMPD3 — GBM

Per-sample scatter of ASIC1 vs FRMPD3 in GBM (Pearson r = 0.37).

Explore this scatter interactively →

Exploration