ASB17

Across TCGA cell cohorts, ASB17 mutation is significantly associated with the drug of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASB17-associated genes across cancer lineages are AZD7969, GSK2801, and PRT062607. Each is linked with ASB17 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB17-to-partner and partner-to-ASB17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AZD7969 grouped by ASB17-low versus ASB17-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB17→partner) and Y-score (partner→ASB17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD7969 →	+0.463	+2.649	.043	.046	3	1
LARGE_INTESTINE	GSK2801 →	+0.338	+2.649	.033	.046	3	1
LARGE_INTESTINE	PRT062607 →	+0.563	+2.769	.025	.040	2	1
LARGE_INTESTINE	JAK1_8709 →	+0.530	+2.649	.006	.046	1	1
LARGE_INTESTINE	LMB_AB3 →	+0.430	+2.649	.015	.046	1	1
LARGE_INTESTINE	50869 →	+0.535	+2.649	.010	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

AZD7969 by ASB17 expression — LARGE_INTESTINE

Explore this box plot interactively →