ASB17

Across TCGA pan-cancer cohorts, ASB17 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of ASB17’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ASB17 RNA is repressed in tumor relative to normal tissue. In most cancer types ASB17 is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

KICH, KIRP, and UCEC are the cancer types where ASB17 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ASB17 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	II,III,IV	−0.317	<.001	7	view →
KIRP	All	All	−0.189	.004	6	view →
UCEC	All	IV	+0.135	.032	6	view →
LUAD	All	All	+0.041	.006	2	view →
LIHC	All	All	+0.020	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

ASB17–KICH

Open the KICH breakdown →