ASB15

Across TCGA cell cohorts, ASB15 RNA expression is significantly associated with the go_rna of many other GO terms, with 453 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ASB15-associated GO terms across cancer lineages are Negative regulation of autophagy, Amyloid-beta clearance by transcytosis, and Negative regulation of macroautophagy. Each is linked with ASB15 in more than 3 cancer types. Because this analysis shows association rather than direction, both ASB15-to-partner and partner-to-ASB15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagy grouped by ASB15-low versus ASB15-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB15→partner) and Y-score (partner→ASB15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of autophagy →	+0.045	+0.006	<.001	.004	3	4
SKIN	Amyloid-beta clearance by transcytosis →	+0.076	+0.006	.003	.004	3	3
SKIN	Negative regulation of macroautophagy →	+0.036	+0.006	.003	.005	3	3
SKIN	Positive regulation of autophagy of mitochondrion →	+0.071	+0.009	<.001	<.001	3	3
SKIN	Cellular response to insulin stimulus →	+0.049	+0.009	.006	.004	3	3
BREAST	Cell-substrate junction organization →	-0.126	-0.025	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 453 associations by consensus.

Negative regulation of autophagy by ASB15 expression — SKIN

Explore this box plot interactively →