ASB15

Across TCGA cell cohorts, ASB15 mutation is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ASB15-associated genes across cancer lineages are NCR1, GSG1L2, and OR7G2. Each is linked with ASB15 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB15-to-partner and partner-to-ASB15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NCR1 grouped by ASB15-low versus ASB15-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB15→partner) and Y-score (partner→ASB15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	NCR1 →	+0.276	+4.906	<.001	.006	3	2
BLOOD_Lymphoma	GSG1L2 →	+0.036	+4.247	<.001	.004	3	2
PANCREAS	OR7G2 →	+0.088	+5.000	<.001	.006	3	1
PANCREAS	MINAR2 →	+0.016	+5.000	<.001	.006	3	1
PANCREAS	DAZ4 →	+0.538	+5.000	<.001	.006	3	1
BLOOD_Lymphoma	LANCL3 →	+0.379	+3.579	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

NCR1 by ASB15 expression — OESOPHAGUS

Explore this box plot interactively →