ASB14

Across TCGA patient cohorts, ASB14 mutation is significantly associated with the RNA expression of many other genes, with 2,919 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ASB14-associated genes across cancer lineages are RNA5SP516, DNAJB5P1, and LINC02790. Each is linked with ASB14 in more than 1 cancer types. Because this analysis shows association rather than direction, both ASB14-to-partner and partner-to-ASB14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP516 grouped by ASB14-low versus ASB14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB14→partner) and Y-score (partner→ASB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP516 →	+0.160	+2.478	<.001	.006	3	2
UCEC	DNAJB5P1 →	+0.144	+1.562	<.001	.008	3	2
UCEC	LINC02790 →	+0.047	+2.063	.001	.009	3	2
UCEC	BTG3-AS1 →	+0.337	+2.254	.004	.005	3	1
UCEC	CCDC163 →	+0.367	+2.823	.007	.001	3	1
UCEC	LINC01943 →	+0.679	+2.491	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,919 associations by consensus.

RNA5SP516 by ASB14 expression — UCEC

Explore this box plot interactively →