ASB14

Across TCGA pan-cancer cohorts, ASB14 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ASB14 data layer compared with 5 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ASB14 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ASB14 expression acts as an unfavorable survival marker, although some lineages such as THYM and PAAD show a favorable association.

ACC, THYM, and LIHC are the cancer types where ASB14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Quartile	II,III,IV	0.110	0.666	<.001	58	view →
THYM	OS	Median	All	1.000	0.770	.003	39	view →
LIHC	OS	Tertile	All	0.588	0.806	<.001	37	view →
PAAD	OS	Quartile	All	0.717	0.315	.007	24	view →
KICH	DFS	Quartile	All	0.569	0.956	.008	24	view →
SKCM	OS	Median	IV	0.810	0.375	.006	23	view →
BRCA	OS	Quartile	III,IV	0.855	0.708	.020	17	view →
LUAD	OS	Quartile	All	0.863	0.676	.007	15	view →
STAD	DFS	Median	IV	0.210	0.570	.015	13	view →
READ	OS	Tertile	II,III,IV	1.000	0.768	.006	13	view →
LGG	DFS	Quartile	All	0.557	0.324	.001	13	view →
KIRC	DFS	Median	II,III,IV	0.365	0.580	.037	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ASB14–ACC (DFS)

Open the ACC breakdown →