ASB14

Across TCGA cell cohorts, ASB14 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,990 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASB14-associated GO terms across cancer lineages are Regulation of telomere maintenance, Microtubule polymerization, and Viral translational termination-reinitiation. Each is linked with ASB14 in more than 16 cancer types. Because this analysis shows association rather than direction, both ASB14-to-partner and partner-to-ASB14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by ASB14-low versus ASB14-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASB14→partner) and Y-score (partner→ASB14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere maintenance →	+0.067	+0.220	.001	.001	3	17
OESOPHAGUS	Microtubule polymerization →	+0.126	+0.183	.006	.004	3	16
BONE	Viral translational termination-reinitiation →	+0.099	+0.246	<.001	<.001	3	16
OESOPHAGUS	Regulation of mRNA splicing, via spliceosome →	+0.099	+0.140	.004	.005	2	16
SOFT_TISSUE	Negative regulation of mRNA splicing, via spliceosome →	+0.085	+0.206	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.177	+0.253	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,990 associations by consensus.

Regulation of telomere maintenance by ASB14 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →