ARVCF

Across TCGA patient cohorts, ARVCF protein abundance is significantly associated with the RNA expression of many other genes, with 14,993 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARVCF-associated genes across cancer lineages are MAPK8IP1, C22orf39, and HMGB1P41. Each is linked with ARVCF in more than 6 cancer types. Because this analysis shows association rather than direction, both ARVCF-to-partner and partner-to-ARVCF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARVCF versus MAPK8IP1 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARVCF→partner) and Y-score (partner→ARVCF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MAPK8IP1 →	+1.082	+0.546	<.001	<.001	3	7
GBM	C22orf39 →	+0.544	+0.470	<.001	<.001	3	6
CCRCC	HMGB1P41 →	+1.110	+0.468	<.001	<.001	3	6
CCRCC	ALDH4A1 →	+1.070	+0.239	.001	.006	3	6
LSCC	PATZ1 →	+0.663	+0.475	<.001	<.001	3	5
LSCC	CADM4 →	+0.999	+0.459	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,993 associations by consensus.

ARVCF vs MAPK8IP1 — UCEC

Explore this scatter interactively →