ARVCF

Across TCGA pan-cancer cohorts, ARVCF RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ARVCF data layer compared with 6 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher ARVCF RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ARVCF expression acts as an unfavorable survival marker, although some lineages such as READ and BLCA show a favorable association.

READ, BLCA, and UCEC are the cancer types where ARVCF RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Quartile	All	0.962	0.720	.001	79	view →
BLCA	OS	Median	II,III,IV	0.507	0.367	.003	60	view →
UCEC	DFS	Tertile	III,IV	0.857	0.656	.002	54	view →
LUSC	DFS	Median	III,IV	0.339	0.961	<.001	34	view →
LUAD	OS	Tertile	II,III,IV	0.483	0.314	.006	30	view →
PAAD	DFS	Quartile	All	0.433	0.157	<.001	26	view →
KIRP	OS	Median	All	0.801	0.579	.005	25	view →
SCLC	DFS	Median	II,III,IV	0.819	0.205	.004	23	view →
KIRC	OS	Median	All	0.842	0.766	.010	21	view →
ACC	DFS	Tertile	II,III,IV	0.121	0.625	.004	19	view →
LIHC	DFS	Tertile	All	0.260	0.567	.002	17	view →
STAD	DFS	Median	All	0.724	0.585	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ARVCF–READ (DFS)

Open the READ breakdown →