ARPC1B

Across TCGA cell cohorts, ARPC1B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,702 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARPC1B-associated GO terms across cancer lineages are Intracellular receptor signaling pathway, Arp2/3 complex-mediated actin nucleation, and Negative regulation of actin filament depolymerization. Each is linked with ARPC1B in more than 12 cancer types. Because this analysis shows association rather than direction, both ARPC1B-to-partner and partner-to-ARPC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular receptor signaling pathway grouped by ARPC1B-low versus ARPC1B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC1B→partner) and Y-score (partner→ARPC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Intracellular receptor signaling pathway →	+0.041	+1.454	.001	.003	3	13
BONE	Arp2/3 complex-mediated actin nucleation →	+0.117	+1.562	<.001	<.001	3	12
BONE	Negative regulation of actin filament depolymerization →	+0.197	+1.913	<.001	<.001	3	10
SOFT_TISSUE	Negative regulation of immune response →	+0.081	+1.951	.001	<.001	3	10
BONE	Barbed-end actin filament capping →	+0.270	+1.866	<.001	<.001	3	10
BLOOD_Leukemia	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	-0.075	-0.751	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,702 associations by consensus.

Intracellular receptor signaling pathway by ARPC1B expression — BONE

Explore this box plot interactively →