ARPC1A

Across TCGA cell cohorts, ARPC1A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,959 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ARPC1A-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and Protein localization to basolateral plasma membrane. Each is linked with ARPC1A in more than 10 cancer types. Because this analysis shows association rather than direction, both ARPC1A-to-partner and partner-to-ARPC1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamic acid carboxylation grouped by ARPC1A-low versus ARPC1A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARPC1A→partner) and Y-score (partner→ARPC1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Peptidyl-glutamic acid carboxylation →	+0.130	+0.986	<.001	<.001	3	11
URINARY_TRACT	Protein carboxylation →	+0.130	+0.986	<.001	<.001	3	11
BLOOD_Myeloma	Protein localization to basolateral plasma membrane →	+0.169	+1.140	.003	.009	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of meiotic cell cycle →	+0.078	+0.789	.003	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of sister chromatid segregation →	+0.112	+0.911	.002	.005	3	7
BLOOD_Leukemia	Actin nucleation →	+0.101	+0.821	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,959 associations by consensus.

Peptidyl-glutamic acid carboxylation by ARPC1A expression — URINARY_TRACT

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