ARMT1

Across TCGA patient cohorts, ARMT1 mutation is significantly associated with the RNA expression of many other genes, with 1,311 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARMT1-associated genes across cancer lineages are TRBV21-1, MTHFD2P3, and RNA5SP413. Each is linked with ARMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMT1-to-partner and partner-to-ARMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRBV21-1 grouped by ARMT1-low versus ARMT1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMT1→partner) and Y-score (partner→ARMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRBV21-1 →	+0.528	+3.852	<.001	.003	3	2
LUAD	MTHFD2P3 →	+0.261	+5.343	<.001	.006	3	2
LUSC	RNA5SP413 →	+0.998	+6.081	<.001	.002	3	2
UCEC	LINC02528 →	+0.347	+2.807	<.001	<.001	3	2
UCEC	RNA5SP418 →	+0.574	+1.970	<.001	.005	3	2
SKCM	NBEAP5 →	+0.240	+5.097	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,311 associations by consensus.

TRBV21-1 by ARMT1 expression — COAD

Explore this box plot interactively →