ARMT1

Across TCGA pan-cancer cohorts, ARMT1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of ARMT1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ARMT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARMT1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, KICH, and STAD are the cancer types where ARMT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARMT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+1.140	<.001	12	view →
KICH	Female	II,III,IV	−1.932	<.001	10	view →
STAD	Male	II,III,IV	+0.847	<.001	8	view →
BLCA	All	III,IV	+0.397	.011	7	view →
BRCA	All	III,IV	+1.102	<.001	6	view →
THCA	Male	II,III,IV	−0.531	.006	6	view →
LIHC	Male	All	+0.535	.001	5	view →
LUSC	Male	All	−0.420	<.001	5	view →
LUAD	Female	II,III,IV	−0.496	.018	3	view →
UCEC	All	All	+0.776	.009	2	view →
READ	All	III,IV	+0.469	.014	2	view →
ESCA	All	All	+0.796	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

ARMT1–HNSC

Open the HNSC breakdown →