ARMC8

Across TCGA patient cohorts, ARMC8 protein abundance is significantly associated with the RNA expression of many other genes, with 9,344 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARMC8-associated genes across cancer lineages are CDV3, ARHGAP5, and LIN52. Each is linked with ARMC8 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARMC8-to-partner and partner-to-ARMC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARMC8 versus CDV3 in LSCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC8→partner) and Y-score (partner→ARMC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDV3 →	+0.462	+0.224	<.001	<.001	3	5
OV	ARHGAP5 →	+0.914	+0.418	.001	.004	3	4
OV	LIN52 →	+0.881	+0.394	<.001	<.001	3	4
LSCC	KPNA1 →	+0.491	+0.237	<.001	<.001	3	4
HNSC	CEP70 →	+0.711	+0.137	<.001	<.001	3	4
HNSC	UMPS →	+0.905	+0.263	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,344 associations by consensus.

ARMC8 vs CDV3 — LSCC

Explore this scatter interactively →